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產(chǎn)品詳細(xì)頁(yè)Huwentoxin-XVI
簡(jiǎn)要描述:Smartox Biotechnology是*一家專門(mén)生產(chǎn)動(dòng)物毒液多肽毒素,用于細(xì)胞離子通道功能研究的生物醫(yī)藥公司。多肽毒素在生物制藥領(lǐng)域具有重要的使用價(jià)值。
- 產(chǎn)品型號(hào):
- 廠商性質(zhì):代理商
- 更新時(shí)間:2024-10-31
- 訪 問(wèn) 量:1472
產(chǎn)品介紹
Huwentoxin-XVI
Huwentoxin-XVI is a selective blocker of N-type Ca2+channels
N型Ca2+通道選擇性阻斷劑
is a 39 amino acids peptide that was discovered from the venom of the Chinese tarantula Ornithoctonus huwena. was shown to be a potent blocker of HVA N-type calcium channels with an IC50 value of 60 nM in rat DRG. The blocking effect appears to be similar to that of ω-conotoxin-GVIA and ω-conotoxin-MVIIA. Neverthelss, differs from GVIA and MVIIA thanks to its greater reversibility and its higher selectivity for N-type over P/Q type than MVIIA.
Huwentoxin-XVI技術(shù)資料
氨基酸序列:
Cys1-Ile-Gly-Glu-Gly-Val-Pro-Cys8-Asp-Glu-Asn-Asp-Pro-Arg-Cys15-Cys16-Ser-Gly-Leu-Val-Cys21-Leu-Lys-Pro-Thr-Leu-His-Gly-Ile-Trp-Tyr-Lys-Ser-Tyr-Tyr-Cys36-Tyr-Lys-Lys-OH
二硫鍵:Cys1-Cys16, Cys8-Cys21 and Cys15-Cys36
長(zhǎng)度 (aa):39
分子式:C196H292N50O56S6
分子量(平均):4437.2 Da
外觀:White lyophilized solid
CAS 號(hào):Not available
來(lái)源:Synthetic
純度:> 98%
產(chǎn)品信息
貨號(hào) | 名稱 | 規(guī)格 |
N/A | 100ug/500ug/1000ug |
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